But even though it's infiltrating pretty much every corner of the wellness world (hi, vegan CBD brownies!) many people still find CBD a little confusing—especially when it comes to figuring out the right way to use it and how to make sure the stuff you're buying is, you know, actually legit. Below, we asked experts to answer the most pressing questions about CBD.


The tricky part is that there's some evidence suggesting CBD works best for pain when combined with a little THC, says Dr. Danesh. "Depending on what type of pain you have, you might be able to do just CBD, but sometimes you need CBD and THC." This makes accessing a product that will actually help you more difficult due to different regulations in each state. In New York, where Dr. Danesh practices, for example, CBD is available over the counter. But as soon as you add THC, you need a prescription.
In a small study published in the journal JCI Insight in 2017, researchers observed that CBD may help prevent stress-related changes in blood pressure. For the study, nine healthy male volunteers took a single dose of either CBD or placebo. Compared to those given the placebo, those treated with CBD had lower blood pressure both before and after experiencing a stressful event.
First, a little background. Industrial hemp was legal in the United States until Congress passed the Marihuana Tax Act in 1937. ("Some of our early presidents grew hemp," notes Sarah Lee Gossett Parrish, a cannabis industry attorney based in Oklahoma.) Nearly 80 years later, the 2014 Farm Bill took the position that states can regulate the production of hemp and, as a result, CBD. Then last year, President Trump signed a new Farm Bill that made it federally legal to grow hemp.
...with due respect, your experience Locsta is almost precisely what happened with my....chihuahua. Degenerative disc disease, excruciating pain, prednisone worked, but couldn't keep her on it..pain killers and muscle relaxants didn't help, really thought I would have to put her down. Chi bloggers suggested CBD; gave PetReleaf a shot--like you, literally within minutes I could see the difference, in days she was pain free and now is back in charge of our world. The real key here is that with my dog, there is zero, nada, chance that there was any placebo effect...

Cannabidiol can be taken into the body in multiple ways, including by inhalation of cannabis smoke or vapor, as an aerosol spray into the cheek, and by mouth. It may be supplied as CBD oil containing only CBD as the active ingredient (no added tetrahydrocannabinol [THC] or terpenes), a full-plant CBD-dominant hemp extract oil, capsules, dried cannabis, or as a prescription liquid solution.[2] CBD does not have the same psychoactivity as THC,[9][10] and may affect the actions of THC.[7][8][9][11] Although in vitro studies indicate CBD may interact with different biological targets, including cannabinoid receptors and other neurotransmitter receptors,[9][12]as of 2018 the mechanism of action for its biological effects has not been determined.[8][9]
Hi Lauren I've just started today with 250mg cbd oil. I'm starting low to see what happens. I've nerve damage across buttocks from a laminectomy. I've not been able to sit for 5 years. I've recently started with a muscle spasm in my left buttock and the muscle above is painful. It is only the first day, also tried a cbd night time tea as well. Do change in muscle pain so tight on my left hand side. How long before felt it starting to work please. I'm trying not to expect changes straightaway. I also take 1100mg gabapentin and 30mg amitriptyline and I hate both of them - they both can cause muscle tightness affecting the nerve. Thank you Lyn
Ive been taking CBD tincture oil for 8 months now. It has made such a positive improvement in my life. I have more energy and I feel better overall. I feel like myself after many years of an overall feeling of lethargy. After taking CBD oil for 6 months, I went to my doctor for a regular check up. All my my bloodwork test results- including A1C and cholesteral- improved. As an added bonus, I lost 25 lbs. All of this without even trying. Adding CBD to my life has given me more energy. I feel like my metabolism has improved. Nowadays, I look forward to each day as what can I do today, while before CBD, my attitude was negative and what do I have to do today. Nothing else in my life has changed. In fact, it has become more stressful due to family illness. But CBD has taken the edge off and continues to be my go-to daily supplement. I use Medterra 500mg tincture oil and take 1/2 a dropper twice a day. Everyone is different, so adjust the amount and strength until you find what works best for you. Definitely do it. Take CBD. Youll be so happy that you did.
I use CBD for relief of PTSDanxietydepressionchronic pain symptoms. This is the best brand I have tried by far. I love that it is clear doesnt feel like I am ingesting motor oil like some other products I have tried. And WOW does it help with my symptoms. My days seem to be feeling less and less like a battle with myself which is already improving my quality of life. It shipped really quickly after I placed my order and I have nothing but good things to say about this product and company. Thank you
Can cannabis help treat psoriasis? The active cannabinoids in cannabis may be an effective treatment for psoriasis. Research shows that they offer potential health benefits that could relieve the symptoms of psoriasis. They may be able to reduce inflammation and itching, control pain, and even heal wounds. Learn more about cannabis for psoriasis here. Read now
^ Jump up to: a b Resstel LB, Tavares RF, Lisboa SF, Joca SR, Corrêa FM, Guimarães FS (January 2009). "5-HT1A receptors are involved in the cannabidiol-induced attenuation of behavioural and cardiovascular responses to acute restraint stress in rats". British Journal of Pharmacology. 156 (1): 181–8. doi:10.1111/j.1476-5381.2008.00046.x. PMC 2697769. PMID 19133999.
I use CBD for relief of PTSDanxietydepressionchronic pain symptoms. This is the best brand I have tried by far. I love that it is clear doesnt feel like I am ingesting motor oil like some other products I have tried. And WOW does it help with my symptoms. My days seem to be feeling less and less like a battle with myself which is already improving my quality of life. It shipped really quickly after I placed my order and I have nothing but good things to say about this product and company. Thank you
Hi, Congrats on finishing chemo & radiation that’s awesome!! I wish you the best of luck!! I was actually wanting to know about dosage for cancer as well..My parents both have recently been diagnosed with cancer 4 months apart and are currently going thru chemo together. I have tried looking for the dosage info but can never find what i’m looking for..I want to try to help lesson the chemo side effects and hopefully kill some of the cancer cells. Can someone please help us?Thank You Christy
Laboratory evidence indicated that cannabidiol may reduce THC clearance, increasing plasma concentrations which may raise THC availability to receptors and enhance its effect in a dose-dependent manner.[23][24] In vitro, cannabidiol inhibited receptors affecting the activity of voltage-dependent sodium and potassium channels, which may affect neural activity.[25] A small clinical trial reported that CBD partially inhibited the CYP2C-catalyzed hydroxylation of THC to 11-OH-THC.[26]
CBD does not appear to have any psychotropic ("high") effects such as those caused by ∆9-THC in marijuana, but may have anti-anxiety and anti-psychotic effects.[10] As the legal landscape and understanding about the differences in medical cannabinoids unfolds, experts are working to distinguish "medical marijuana" (with varying degrees of psychotropic effects and deficits in executive function) – from "medical CBD therapies” which would commonly present as having a reduced or non-psychoactive side-effect profile.[10][59]
Hi Marilyn, I would recommend a topical lotion or salve to start for instant relief.. Maybe 250 to 300 mg tincture to see how you feel. For me, the salve took the pain in my hands away in under a minute. I didn't notice how much the tincture worked until I forgot to take on vacation. Pain that was pretty much gone but came back, I was tired, grumpy and felt horrible. It works, just need to find right product and dosage for you.

In response to the FDA’s historic decision, the Drug Enforcement Administration (DEA) announced in September 2018 that it had removed Epidiolex from Schedule I classification, a category reserved for dangerous drugs with no medical value. Henceforth, Epidiolex would be considered a Schedule V drug, the least dangerous designation under the Controlled Substances Act.
Hi, I have had spondylolisthesis since age 11 which left me with extreme nerve pain...restless leg syndrome. Had 3 spinal ops and also had hip surgery 2 years ago. have asthma and hypothyroidism. I can deal with everything else but this nerve pain is insane. Used Gabapentin for 9 years and now its not in the market in Nairobi, Kenya where I live. Am on Lyrica, which is not working. I started Cbd oil in August but now found my body has become immune to the effects of pain releif I was getting. Can anyone suggest what strength oil/cbd supplement I should aim for? Currently am making flapjacks with weed, have one every night but this makes me high which I dont want. I still wake up in pain at night, please help.
Figuring out how much CBD oil to take can feel like trying to navigate through a complicated maze. The sheer volume of CBD brands on the market can create confusion for consumers, and when you take a closer look, it’s not difficult to understand why. Not only do vendors use different source materials (CBD-rich cannabis vs. industrial hemp, different strains, etc.), but they also implement different extraction techniques .
Laboratory evidence indicated that cannabidiol may reduce THC clearance, increasing plasma concentrations which may raise THC availability to receptors and enhance its effect in a dose-dependent manner.[23][24] In vitro, cannabidiol inhibited receptors affecting the activity of voltage-dependent sodium and potassium channels, which may affect neural activity.[25] A small clinical trial reported that CBD partially inhibited the CYP2C-catalyzed hydroxylation of THC to 11-OH-THC.[26]
A co-worker of mine recommended this product because her husband started using it and noticed more energy and significantly reduced his chronic pain symptoms almost immediatelyafter starting to use this product. She said she was able to fall asleep more easily on night one, and she woke up with energy the next morning before her alarm went off. My husband has horrible neck pain because of an accident a couple of years ago. I finally convinced him to try it out. I will update or do a new review once hes tried it out.

Did you get an answer for this? I have the exact same scenario. I'm treating my TN with Tegretol, and recently tried CBD. I think I took too much and there are some weird drug interactions with Tegretol and I felt quite stoned....was alone and talking to myself in my head thinking I was Einstein. It freaked me out a bit but I think I took too much. I'm trying lower doses again as recently my TN seems to be resisting the meds, although I have had a lot of emotional stress, which seems to be a trigger. Thanks!! Anna
Mike, what kind of breast cancer (invasive ductal, I presume)? How many of her lymph nodes were positive? How big was the primary tumor? Reason I ask is that in women with Stage I or IIA tumors that are estrogen-and progesterone-receptor-positive and HER2-negative (ER+/PR+/HER2-) with three or fewer positive lymph nodes, there is a genomic assay test on a sample of the tumor, called OncotypeDX, that will tell doctors whether chemo is necessary or would even work at all. Medicare covers that test 100%.That type of breast cancer mentioned above, which I had as Stage IA, is treated in postmenopausal women with anti-estrogen drugs called aromatase inhibitors(aka AIs: anastrazole, letrozole, or exemestane)which have as a side effect joint pain. CBD oil is effective for this joint pain it is not, I repeat, NOT a substitute for chemo, radiation or these anti-estrogen drugs.So don’t assume your mom’s cancer will require chemo; but if it does, CBD helps with those side effects as well. If she lives in a state where medical marijuana is legal, there are doctors who sub-specialize in certifying applications for a medical marijuana card, and in the interim before the card is issued can advise as to the appropriate dose of CBD oil (legal and over-the-counter in all 50 states). Some (though not most) medical oncologists will certify their own patients’ medical marijuana card applications so she need not seek out another doctor; and will advise the appropriate dose for her symptoms. Once she gets her card, the “budtenders” in the licensed dispensaries can advise her as to the right CBD product (with or without THC), strength, and dosage. If she lives in a state where recreational weed is legal, the “budtenders” in the marijuana shops can steer her to the right strength of CBD oil and the right dosage.
No restrictions and our always-free shipping mean for unparalleled access to some of the world’s best in organic CBD’s. In addition, we are proud to say that we are quite knowledgeable in the CBD field and CBD applications as opposed to many out there, just trying to sell a product. If you need help deciding which CBD line is best for your intended application, we are always happy to explain the options to your fullest understanding.
There is no scientific evidence or research on CBD as an effective treatment for migraine—in large part because it has not been formally studied. However, it may still be a viable topical option for some patients with joint and muscle pain associated with migraine. “If you have a lot of neck pain or soreness, it is perfectly reasonable to use CBD oil. It may even prevent nausea and vomiting,” Dr. Silberstein says.
Mike, what kind of breast cancer (invasive ductal, I presume)? How many of her lymph nodes were positive? How big was the primary tumor? Reason I ask is that in women with Stage I or IIA tumors that are estrogen-and progesterone-receptor-positive and HER2-negative (ER+/PR+/HER2-) with three or fewer positive lymph nodes, there is a genomic assay test on a sample of the tumor, called OncotypeDX, that will tell doctors whether chemo is necessary or would even work at all. Medicare covers that test 100%.That type of breast cancer mentioned above, which I had as Stage IA, is treated in postmenopausal women with anti-estrogen drugs called aromatase inhibitors(aka AIs: anastrazole, letrozole, or exemestane)which have as a side effect joint pain. CBD oil is effective for this joint pain it is not, I repeat, NOT a substitute for chemo, radiation or these anti-estrogen drugs.So don’t assume your mom’s cancer will require chemo; but if it does, CBD helps with those side effects as well. If she lives in a state where medical marijuana is legal, there are doctors who sub-specialize in certifying applications for a medical marijuana card, and in the interim before the card is issued can advise as to the appropriate dose of CBD oil (legal and over-the-counter in all 50 states). Some (though not most) medical oncologists will certify their own patients’ medical marijuana card applications so she need not seek out another doctor; and will advise the appropriate dose for her symptoms. Once she gets her card, the “budtenders” in the licensed dispensaries can advise her as to the right CBD product (with or without THC), strength, and dosage. If she lives in a state where recreational weed is legal, the “budtenders” in the marijuana shops can steer her to the right strength of CBD oil and the right dosage.
Green Roads CBD oil products are both easy to use and offer all of the benefits associated with CBD and hemp. CBD oil can be used sublingually via a dropper, or it can be added to your food and beverages which is why most new users have made it their go-to CBD product of choice. Every item in our collection of CBD oils has been formulated by our licensed pharmacist of 25 plus years and then tested by independent labs to ensure that we comply with all industry standards and regulations.
CBDPure oils are made with non-GMO hemp, grown in Colorado by local farmers. Our hemp oil is minimally processed by following the highest organic standards at every step of our growing, harvesting, and bottling process. When you buy a CBDPure product, you are buying the purest CBD oil from natural sources, that is 100% free of any synthetic or artificial ingredients. We test every batch of oil that we process to ensure that it meets the purity standards that we demand.
^ Hayakawa K, Mishima K, Nozako M, Ogata A, Hazekawa M, Liu AX, Fujioka M, Abe K, Hasebe N, Egashira N, Iwasaki K, Fujiwara M (March 2007). "Repeated treatment with cannabidiol but not Delta9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance". Neuropharmacology. 52 (4): 1079–87. doi:10.1016/j.neuropharm.2006.11.005. PMID 17320118.
Purchased the 3000mg tincture bottle, have been using this in the mornings and after working out at night. Working a desk job, my back can become stiff and achy easily if proper posture is not maintained. This coupled with working out quickly lead to days where it just hurt to get out of bed or even bend over to tie my shoes in the morning. After the first day of trying this out, my back pain was gone. And I mean gone. I would encourage anyone who has any pain at all anywhere to give this a try. The anti-inflammation results are great. I’ll admit I was skeptical at first and wanted to make sure I did some research before buying, but the results really do speak for themselves. 10/10 and would 100% recommend. Very happy I found this when I did.
The dosages mentioned do not take into account the strength of the tincture. I have Elixinol 300, I took 1/2 dropper (0.5ml, which offers 5mg of CBD) as indicated on the bottle and felt severely nauseous for 3 hours thereafter. There is no way I cold take this dose twice per day, as recommended on the bottle. The high dosages on this site must surely be for much weaker concentrations?
CBD (Cannabidiol) is a potent, non-psychoactive cannabinoid found in hemp oil. It is typically extracted from industrial hemp plants that are naturally high in CBD and other phytochemicals. It is the most prevalent of over 80 different cannabinoids found in natural hemp. It is commonly used for its therapeutic properties. Cannabidiol is responsible for a wide-range of positive health benefits through its interaction with the body's own endocannabinoid system.

The tricky part is that there's some evidence suggesting CBD works best for pain when combined with a little THC, says Dr. Danesh. "Depending on what type of pain you have, you might be able to do just CBD, but sometimes you need CBD and THC." This makes accessing a product that will actually help you more difficult due to different regulations in each state. In New York, where Dr. Danesh practices, for example, CBD is available over the counter. But as soon as you add THC, you need a prescription.

We’ve been selling MEDterra in our store now for a few months. Can’t keep our shelves stocked. We sell out weekly! It’s our number thing we sell in our smoke shop. I have a lot of in depth conversations with my clients about the product and how it is helping them and their pets and this stuff is truly amazing! And now I’m doing to treat an old shoulder injury and I feel GREAT! Thanks MEDterra! Talk to you next week when I order more :)


There's no question that CBD is the buzzy wellness product of the moment. If you live in a state where it's currently legal, you might feel like CBD has gone from being sort of around to absolutely everywhere all at once. Coffee shops sell CBD lattes, spas offer CBD facials, beauty companies are rushing to release lotions with CBD or hemp oils in their formulas. And everyone from your anxious coworker to your arthritis-suffering dad wants to get their hands on some CBD gummies.

In the United States, non-FDA approved CBD products are classified as Schedule I drugs under the Controlled Substances Act.[62] This means that production, distribution, and possession of non-FDA approved CBD products is illegal under federal law. In addition, in 2016 the Drug Enforcement Administration added "marijuana extracts" to the list of Schedule I drugs, which it defined as "an extract containing one or more cannabinoids that has been derived from any plant of the genus Cannabis, other than the separated resin (whether crude or purified) obtained from the plant."[63] Previously, CBD had simply been considered "marijuana", which is a Schedule I drug.[62][64]
There are two possible exceptions to this. The first is that some people, for unknown reasons, just react differently to CBD. According to Dr. Chin, about 5% of people say they feel altered after taking CBD. "Usually they're the same people who have side effects from Advil or Tylenol," she says. You never know how your body will react to any new supplement, so when taking CBD for the first time, do so safely under supervision.
Hi, I have had spondylolisthesis since age 11 which left me with extreme nerve pain...restless leg syndrome. Had 3 spinal ops and also had hip surgery 2 years ago. have asthma and hypothyroidism. I can deal with everything else but this nerve pain is insane. Used Gabapentin for 9 years and now its not in the market in Nairobi, Kenya where I live. Am on Lyrica, which is not working. I started Cbd oil in August but now found my body has become immune to the effects of pain releif I was getting. Can anyone suggest what strength oil/cbd supplement I should aim for? Currently am making flapjacks with weed, have one every night but this makes me high which I dont want. I still wake up in pain at night, please help.
Various strains of "medical marijuana" are found to have a significant variation in the ratios of CBD-to-THC, and are known to contain other non-psychotropic cannabinoids.[60] Any psychoactive marijuana, regardless of its CBD content, is derived from the flower (or bud) of the genus Cannabis. Non-psychoactive hemp (also commonly-termed industrial hemp), regardless of its CBD content, is any part of the cannabis plant, whether growing or not, containing a ∆-9 tetrahydrocannabinol concentration of no more than 0.3% on a dry-weight basis.[61] Certain standards are required for legal growing, cultivating, and producing the hemp plant. The Colorado Industrial Hemp Program registers growers of industrial hemp and samples crops to verify that the dry-weight THC concentration does not exceed 0.3%.[61]
In fact, the U.S. Food and Drug Administration (FDA) approved Epidiolex (a drug made with a purified form of CBD oil) in June 2018 for the treatment of seizures associated with two rare and severe forms of epilepsy in patients 2 years of age and older. These two epilepsy forms are known as Lennox-Gastaut syndrome and Dravet syndrome. Epidiolex is the first FDA-approved drug that contains a purified drug substance derived from marijuana.
These policies vary widely. Marijuana and CBD are currently fully legal for both medicinal and recreational purposes in Alaska, California, Colorado, Maine, Massachusetts, Michigan, Nevada, Oregon, Vermont, Washington, and Washington D.C. In 23 states, it's legal in some form, such as for medicinal purposes. Another 14 states permit just CBD oil. But both are illegal in Idaho, Nebraska, and South Dakota. For more information, the organization Americans for Safe Access has a helpful guide to the specific laws in each state.
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